This month, Italy introduced a new tool in its fight against coronavirus and other health crises: a hospital train. Capable of treating and transporting as many as 21 critically ill patients, the newly equipped train is currently located at Milan’s Greco Pirelli railway station, in Italy’s worst hit region, Lombardy. With pressure on regular hospitals reduced since Italian cases of Covid-19 peaked between late March and early April, the train is not due to be deployed immediately. It could, however, be used to relieve any regions hit hard in a second wave. It is one of several converted trains in western Europe since the beginning of the pandemic – with one mobile clinic already being credited for saving lives.
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It is France, however, that has done most to use railways to help manage its pandemic response. In March, CityLab reported on its plan to use a high-speed TGV train to transfer Covid-19 patients from the particularly stricken Grand Est region flanking the German border to hospitals in western France. Since then, carrier SNCF has conducted patient transfers: four from the Grand Est region, and five from Paris to hospitals in Brittany and Aquitaine. The transfers seem to have had an effect.
Health authorities in Brittany announced this month that of 84 patients transferred by hospital train to the region, 57 had already improved enough to return to their home regions, and 17 released from hospital. Six patients transferred have since died, nine remain in intensive care, and a further 12 have left emergency care but remain in the hospital. It’s unclear whether or not these outcomes are better than if the patients had all remained in the regions where they were first admitted to the hospital, but it seems likely that the transfers gave a better chance of recovery to both the patients on the trains and the patients left behind in hospitals.
https://www.citylab....e-spain/612328/COVID-19 patients who undergo surgery are at increased risk of postoperative death
https://www.eurekale...b-cpw052920.phpOlder men worry less than others about COVID-19
https://www.eurekale...u-omw052920.php This week in the journal Frontiers, researchers describe a single function that accurately describes all existing available data on active cases and deaths—and predicts forthcoming peaks. The tool uses q-statistics, a set of functions and probability distributions developed by Constantino Tsallis, a physicist and SFI External Professor Emeritus. Tsallis worked on the new model together with Ugur Tirnakli, a physicist at Ege University, in Turkey.
“The formula works in all the countries in which we have tested,” says Tsallis.
Neither physicist ever set out to model a global pandemic. But Tsallis says that when he saw the shape of published graphs representing China’s daily active cases, he recognized shapes he’d seen before—namely, in graphs he’d helped produce almost two decades ago to describe the behavior of the stock market.
“The shape was exactly the same,” he says. For the financial data, the function described probabilities of stock exchanges; for COVID-19, it described daily the number of active cases—and fatalities—as a function of time.
Modeling financial data and tracking a global pandemic may seem unrelated, but Tsallis says they have one important thing in common. “They’re both complex systems,” he says, “and in complex systems, this happens all the time.” Disparate systems from a variety of fields—biology, network theory, computer science, mathematics—often reveal patterns that follow the same basic shapes and evolution.
https://www.santafe....vid-19-pandemichttps://www.scienced...00529150605.htm A combination of genetic shuffling and evolutionary selection of near-identical genetic sequences among specific bat and pangolin coronaviruses may have led to the evolution of SARS-CoV-2 and its introduction into humans, a new study suggests. The results also showed that the virus' entire receptor binding motif (RBM), a component that plays a key role in viral entry into host cells, was introduced through recombination with pangolin coronaviruses. The study joins ongoing efforts to identify the source of the virus that causes COVID-19, which is critical for informing efforts to establish proper animal models, discover new drugs and vaccines, and ultimately prevent the rise of future zoonotic diseases.
https://www.eurekale...t-spe052920.phpWorld Health Organization sends 31 tons of aid to Yemen
https://www.aa.com.t...o-yemen/1858498 The UN humanitarian chief urgently appealed for $2.4 billion to help millions of people in Yemen cope with the conflict and coronavirus, saying programs are already being cut and the situation is “alarming.”
Mark Lowcock told a UN briefing Thursday that the UN received $3.2 billion last year for Yemen because countries in the region — including Saudi Arabia and the UAE who are involved in the conflict — stepped up.
This year, the UN has appealed for about $3.4 billion but as of Wednesday it had only received $516.6 million, just over 15%. The Saudis pledged $525 million in early April and Lowcock said he hopes it will quickly be turned into cash.
The United Nations and Saudi Arabia are co-hosting a video pledging conference for Yemen on Tuesday and Lowcock said he has been on the phone with Persian Gulf leaders in recent days but doesn’t know what they’re going to do. The collapse in oil prices because of the pandemic may be spurring internal discussions, he said.
https://english.alar...covid-19-relief Scientists do not yet know if Severe Acute Respiratory Syndrome Coronavirus 2, or SARS-CoV-2—the virus that causes COVID-19—can be transmitted by blood transfusion. But given the unknowns around this new pathogen, researchers at Colorado State University used existing technologies to show that exposing the coronavirus to riboflavin and ultraviolet light reduces pathogens in human plasma and whole-blood products.
The study, "Pathogen reduction of SARS-CoV-2 virus in plasma and whole blood using riboflavin and UV light," was published May 29 in PLOS ONE.
Dr. Izabela Ragan, postdoctoral fellow in the Department of Biomedical Sciences at CSU, said the research team tackled one of the big questions about the novel coronavirus: If the pathogen can spread through blood or by donating blood, would it be possible to kill the virus?
"The research we conducted answers that question: yes, you can," said Ragan. "We eliminated a huge amount of virus and we could not detect the virus post-treatment."
https://medicalxpres...ens-plasma.htmlIsrael arrests imam of Al-Aqsa Mosque as Palestinians run out of patience with coronavirus closure
https://english.alar...-al-aqsa-mosque The World Health Organization (WHO), Costa Rica and other partners on Friday officially launched a COVID-19 Technology Access Pool, an initiative aimed at making vaccines, tests, treatments and other health technologies to fight COVID-19 accessible to all.
WHO said in a press release that the Pool was first proposed in March by President Carlos Alvarado of Costa Rica and so far has been supported by over 30 countries and multiple international partners and institutions.
Speaking at a virtual media briefing on Friday, WHO Director-General Tedros Adhanom Ghebreyesus said that the COVID-19 Technology Access Pool, or C-TAP, is a sister initiative of the ACT Accelerator, another plan that WHO and partners launched a month ago to speed up the development, production and equitable distribution of vaccines, diagnostics and therapeutics for COVID-19.
"Through C-TAP, we are inviting companies or governments that develop an effective therapeutic to contribute the patent to the Medicines Patent Pool, which would then sub-license the patent to generic manufacturers," Tedros said.
http://www.ecns.cn/n...pi8641501.shtml A front-running Covid-19 vaccine candidate being developed in China is expected to be available as soon as the end of this year, according to a report published in the official Wechat account of the State-owned Assets Supervision and Administration Commission.
The vaccine, jointly developed by the Beijing Institute of Biological Products and China National Biotec Group Co., has completed phase II testing and may be ready for the market at the end of this year or early next year, said the report.
The production line for the vaccine will be fully disinfected and closed in preparation for output to start Saturday, and will have a full manufacturing capacity of 100 million-120 million vaccines each year.
Drugmakers are racing to develop a cure for the contagion that has so far killed at least 365,000 people. More than 100 vaccines for the virus are being developed globally, but only a handful have made it to the crucial and final human clinical trial stage, with Chinese scientists leading the way.
https://www.bloomber...utput-this-yearOil And Gas Rig Count Falls For Ninth Straight Week
https://oilprice.com...aight-Week.html But The Intercept, as the result of an investigation by animal rights group Direct Action Everywhere, or DxE, has obtained video footage of the procedure and the resulting carnage that occurred at one of the company’s facilities in mid-May. Additionally, a whistleblower employed by Iowa Select has provided extensive details to The Intercept about the extraordinary methods now being employed to kill pigs — agonizingly and over the course of many hours — in increasingly large numbers.
What prompted both the DxE investigation and the whistleblower to come forward is Iowa Select’s recent adoption of the mass-extermination method known as “ventilation shutdown,” or VSD. Under this method, pigs at the company’s rural Grundy County facility are being “depopulated,” using the industry’s jargon, by sealing off all airways to their barns and inserting steam into them, intensifying the heat and humidity inside and leaving them to die overnight. Most pigs — though not all — die after hours of suffering from a combination of being suffocated and roasted to death. The recordings obtained by The Intercept include audio of the piercing cries of pigs as they succumb. The recordings also show that some pigs manage to survive the ordeal — but, on the morning after, Iowa Select dispatches armed workers to enter the barn to survey the mound of pig corpses for any lingering signs of life, and then use their bolt guns to extinguish any survivors.
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During the pandemic, mass slaughter has become commonplace at factory farms, even though many of these farms are not where large-scale killing is meant to occur. In normal times, the animals would be transported to slaughterhouses and killed there in ways that, at least in theory, minimize the cruelty by accelerating the death process. But mass killings that radically deviate from the normal slaughterhouse process are now rampant in this industry and are expected to increase. “At least two million animals have already reportedly been culled on farm, and that number is expected to rise,” The Guardian reported on April 29. Officials in Iowa “have warned that producers could be forced to kill 700,000 pigs a week due to meat plant slowdowns or closures.”
long & w/vid
https://theintercept...wn-coronavirus/SHOCKING: Partier From Lake of the Ozarks Petri Dish Pool Party Has Tested Positive for Coronavirus
https://www.mediaite...or-coronavirus/All the COVID-19 treatments currently in clinical trials
long
https://www.digitalt...reatments-list/ Global pharmaceutical major Pfizer believes that a vaccine to prevent Covid-19 could be ready by the end of October, the company's CEO Albert Bourla said.
Pfizer is conducting clinical trials in the US and Europe for the BNT162 vaccine programme to prevent Covid-19 in collaboration with German mRNA company BioNTech.
Bourla made the comments while participating at a virtual event organised by the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) this week.
"If things go well and the stars are aligned, we will have enough evidence of safety and efficacy for us to feel comfortable, for the FDA (US Food and Drug Administration) to feel comfortable, and for the EMA (European Medicines Agency) to feel comfortable, to have a vaccine around the end of October," Bourla was quoted as saying at the event by FierceBiotech.
https://www.khaleejt...aims-pfizer-ceoCanada bans cruise ship visits until October
https://medicalxpres...ip-october.htmlThe anti-vax movement is using growing hesitation around the coronavirus vaccine to attract more people
https://www.business...-vaccine-2020-5 Whole Foods has fired a California employee who created a running count of COVID-19 cases in company’s US supermarkets because neither Amazon nor Whole Foods would make the information publicly available.
Katie Doan, who worked at the Tustin Whole Foods in Orange County for three years, says she was fired on Wednesday for “time theft” when she took a 45 minute break to recover from a panic attack. For many Whole Foods employees and other grocery store workers around the country, working at the company has been stressful and anxiety-inducing, in part because of the ever-present risk of catching COVID-19. Motherboard viewed a copy of the terms of her separation from the company.
https://www.vice.com...ronavirus-cases