26251 replies to this topic

[Victoria Watcher]

i misread that.  and edited.

 

they found 16 unvaccinated people in ICU.

Edited by Victoria Watcher, 05 August 2021 - 07:05 AM.

[Mike K.]

Wasn’t it 16 who were vaccinated?

Interesting they mention comorbitites as factors for them, but not the others.

[Victoria Watcher]

oh yes that's what i meant.

[Victoria Watcher]

Quebec’s Premier says his province will introduce a vaccine passport system to prevent a fourth wave.

 

Francois Legault says Health Minister Christian Dubé will announce details in the coming days about how the system will work and when it will begin.

 

In early July, Health Minister Dubé said a vaccine passport would be put in place by September in areas where COVID-19 outbreaks occur, requiring people to prove they are vaccinated to enter places such as gyms and bars and where COVID-19 transmission is high.

 

 

 

https://www.cbc.ca/n...sport-1.6130699

Edited by Victoria Watcher, 05 August 2021 - 07:44 AM.

[amor de cosmos]

B.C. records 342 new cases of COVID-19, the highest daily case count since May 27
There are 55 people in hospital with the disease, 23 of whom are in intensive care
https://www.cbc.ca/n...aug-4-1.6128995
 
The study, titled “Examining the potential benefits of the influenza vaccine against SARS-CoV-2: A retrospective cohort analysis of 74,754 patients,” was published in the peer-reviewed scientific journal PLoS One on August 3. This was the largest study of its kind and analyzed deidentified patient records from around the world, which strongly suggested that the annual flu shot reduces the risks of stroke, sepsis, and DVT in patients with COVID-19. Patients with COVID-19 who had been vaccinated against the flu were also significantly less likely to visit the emergency department and be admitted to the intensive care unit.
https://www.newswise...ts-of-covid-19/

 

Newswise — A KAIST immunology research team found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cells. This study provides new insights for understanding dynamic changes in immune responses to COVID-19. 

 

In the early phase of COVID-19, SARS-CoV-2 infected lung tissue and the immediate defense system is activated. This early and fast response is called ‘innate immunity,’ provided by immune cells residing in lungs. Macrophages are major cell types of the innate immune system of the lungs, and newly differentiated macrophages originating from the bloodstream also contribute to early defenses against viruses.

 

Professor Su-Hyung Park and his collaborators investigated the quantitative and qualitative evaluation of immune responses in the lungs of SARS-CoV-2 infected ferrets. To overcome the limitations of research using patient-originated specimens, the researchers used a ferret infection model to obtain SARS-CoV-2 infected lungs sequentially with a defined time interval. 

 

The researchers analyzed the 10 subtypes of macrophages during the five-day course of SARS-CoV-2 infection, and found that infiltrating macrophages originating from activated monocytes in the blood were key players for viral clearance as well as damaged lung tissue. Moreover, they found that the differentiation process of these inflammatory macrophages resembled the immune responses in the lung tissue of severe COVID-19 patients.

https://www.newswise...uring-covid-19/

 

PITTSBURGH – SARS-CoV-2 nanobodies—microscopic molecules developed at the University of Pittsburgh School of Medicine that neutralize the virus in animals—are remarkably active against mutations found in variants, including Delta, according to new research by Pitt and Case Western Reserve University scientists.

 

The findings, announced today in Nature Communications, describe three different mechanisms by which the nanobodies disarm the virus, blocking it from infecting cells and causing COVID-19. The near-atomic-level structural analysis provides guidance for the development of future vaccines and therapeutics that may work against a wide variety of coronaviruses—including variants not yet in circulation.

 

“This is the first time anyone has systematically classified ultrapotent nanobodies based on their structure,” said senior author Yi Shi, Ph.D., assistant professor of cell biology at Pitt. “By doing this, we’ve not only provided details on the mechanisms our nanobodies use to defeat SARS-CoV-2, but also revealed directions for how to design future therapeutics.”

 

Late last year, Shi and his team announced that they’d extracted tiny, but extremely powerful, SARS-CoV-2 antibody fragments from llamas, which could be fashioned into inhalable therapeutics to prevent and treat COVID-19. Since then, preclinical studies have verified that the potent nanobodies prevent and treat severe COVID-19 in hamsters, reducing virus particles in their respiratory tracts by a million-fold compared to placebo.

 

In this latest study, Shi partnered with Pitt structural biologists Cheng Zhang, Ph.D., and James Conway, Ph.D., as well as pharmacologists, structural biologists and biochemists at Case Western Reserve, to use high-resolution cryoelectron microscopy to observe exactly how the nanobodies interact with the SARS-CoV-2 virus to stop it from infecting cells and discover how mutations found in variants may affect nanobody interactions.

https://www.upmc.com...obody-structure

https://www.scienced...10803175302.htm

Research shows many with mild COVID-19 infections still experience long-term symptoms
https://medicalxpres...m-symptoms.html

France to offer COVID booster shots to elderly, vulnerable from September
https://medicalxpres...ts-elderly.html
 

MOSCOW, August 5. TASS/. The global number of coronavirus cases has exceeded 200.2 mln, according to TASS estimates based on data from governments, experts and the media.
 
The share of those infected has passed 2.5% of the global population, estimated by the United Nations Population Fund at 7,875,000,000, which means that one in 40 people in the world have been diagnosed with COVID-19. Five countries account for about half of those infected, including the United States (35.3 mln), India (31.8 mln), Brazil (20 mln), Russia (6.4 mln) and France (6.3 mln).
 
Western European countries reported a new wave of the coronavirus in the early summer but have managed to stabilize the situation over the past few weeks. In addition, the number of daily cases skyrocketed in North America and Asia in July.
 
The total coronavirus death toll has passed 4.25 mln, meaning that 2.1% of coronavirus patients have died. The United States accounts for the majority of fatalities (615,000), followed by Brazil (560,000) and India (426,000). The highest mortality rates have been recorded in Yemen (19.5%) and Peru (9.3%).

https://tass.com/world/1322949

Norway Now Has Fewer Deaths From COVID-19 Than Ordinary Flu
https://sputniknews....n-ordinary-flu/
 

JAKARTA : Indonesia pulled out of recession in the second quarter, reporting its strongest annual growth rate in 17 years, but analysts warned its economic recovery will suffer a setback due to a recent surge in COVID-19 infections.

Southeast Asia's largest economy grew 7.07per cent in the April-June quarter compared with a year earlier, its first expansion in five quarters, Statistics Indonesia reported on Thursday.

The expansion rate beat a 6.57per cent forecast by analysts in a Reuters poll and was the highest since the October-December quarter of 2004. The first quarter's contraction was revised to 0.71per cent.

Surging exports - including impressive 56per cent growth in commodity shipments - a rebound in consumption and investment, and bigger government spending boosted activity.

However, the statistics bureau said the high growth rate was also due to low base effects when compared to the weak pandemic-stricken second quarter last year.

Despite the better-than-expected outcome, analysts are downgrading their outlooks for the economy due to the virus' resurgence and mobility restrictions imposed since July.

https://www.channeln...ecovery-2094396
 

The recent COVID-19 outbreak in Hunan province has been traced to three tourists from outside the province who traveled to the city of Zhangjiajie in Hunan via Nanjing Lukou International Airport in Jiangsu's provincial capital.

The majority of recent cases around China have been linked to the airport in Nanjing.

The three tourists arrived in Zhangjiajie on July 17 after passing through the airport. Zhangjiajie, a famous tourist attraction in Hunan, has since been linked to infections in several cities including Wuhan, Hubei province, and Beijing.

They stayed in Zhangjiajie until July 23, Gao Lidong, director of the Hunan Provincial Center for Disease Control and Prevention, said on Wednesday. They then went to Hunan's Xiangxi Tujia and Miao autonomous prefecture for a day.

A tour guide in Zhangjiajie and some tourists from Beijing and Chengdu, Sichuan province, got infected in Zhangjiajie while taking part in activities that included having breakfast in hotels, Gao said.

The tourists from Chengdu who were infected in Zhangjiajie transmitted the virus to several people who shared the same sightseeing boat in Changde, Hunan, on July 24.

"Genome sequencing analysis shows all patients in Hunan are infected with the delta variant, which is highly homologous with the outbreak in Jiangsu province," Gao said.

http://www.ecns.cn/n...ct3741704.shtml
 

The sudden shutdown of the Fort Detrick lab in the United States and the pneumonia outbreak that followed are far from coincidental and should be studied in the scope of the ongoing investigation into the pandemic's origins, a Russian political observer has said. 
 
In his article published in the Free Media online newspaper on Saturday, Sergei Plotnikov outlined some striking events that followed after the closure of the prominent military biological lab in Maryland.
 
Alongside a lack of transparency from the U.S. government in relation to the closure, there was little coverage of the unknown pneumonia outbreak that happened in two nursing homes in July 2019, which were "coincidentally" located close to the military base, Plotnikov wrote.
 
While the disease continued to spread throughout the United States with its cause and origins remaining unknown, the U.S. lab remained closed and was not involved in any research, he added.
 
Local authority quickly linked the unprecedented outbreak to e-cigarette use as victims in Wisconsin, northern Virginia and later other parts of the country continued to suffer from the lung disease.
 
Specialists from the U.S. National Institutes of Health believe that the coronavirus, which was unknown at that time, started spreading in the United States in the fall of 2019, according to Plotnikov.
 
"Some of the 24,000 blood samples collected in early 2020 from different places in the United States already had antibodies against COVID-19," he wrote.

http://www.ecns.cn/n...ct3741745.shtml

The defense secretary is considering making COVID-19 vaccines mandatory for all active-duty US troops, report says
https://www.business...oops-cnn-2021-8
 

A Texas GOP official died with COVID-19 days after sharing a meme questioning the usefulness of coronavirus vaccines.
 
H. Scott Apley, a member of the State Republican Executive Committee in Texas, died in hospital on Wednesday morning.
 
He tested positive for COVID-19 on Sunday, according to a fundraising page set up to cover his medical bills and, later, his funeral expenses. As of early Thursday it had raised $28,000.
 
Apley, who was also a member of the Dickinson County Council, was a new father, according to the page. His wife had also tested positive for the virus.
 
The Texas Republican Party confirmed his death on Wednesday.
 
"I am very saddened to report that H Scott Apley passed away last night at about 3 am," the page said.
 
"He leaves behind his wife, Melissa, who is COVID positive, as well as their infant son Reid."
 
Five days before his death, Apley shared a meme on Facebook which questioned the usefulness of COVID-19 vaccines, the Daily Beast first reported.
 
The post was a screenshot of a tweet which read: "In 6 months, we've gone from the vax ending the pandemic — to you can still get covid even if vaxxed — to you can pass covid onto others even if vaxxed — to you can still die of covid even if vaxxed — to the unvaxxed are killing the vaxxed."

https://www.business...covid-19-2021-8

[Victoria Watcher]

The beginning of Vancouver Island’s fourth wave is here

https://www.capitald...th-wave-is-here

[max.bravo]

The beginning of Vancouver Island’s fourth wave is here

https://www.capitald...th-wave-is-here

 

But will they issue another state of emergency and reinstate lockdown measures across the province? Doing so would be an admission that vaccinations aren't as effective as first sold. However you can't argue with the fact we have more cases today than the same day 1 year ago.

[VIResident]

But will they issue another state of emergency and reinstate lockdown measures across the province? Doing so would be an admission that vaccinations aren't as effective as first sold. However you can't argue with the fact we have more cases today than the same day 1 year ago.

 

Having the vaccine keeps me alive, I'm good with that. 

[max.bravo]

Having the vaccine keeps me alive, I'm good with that.

I’m unaltered (ie., unvaxed) and still kickin. Can you tell me the absolute difference in risk of death from covid between you and me? Assuming we are both under 50.

I’ve got ivermectin on hand in case I catch it. Zero risk of vaccine side effects. It’s a logical choice.

Edited by max.bravo, 05 August 2021 - 09:21 AM.

[Rob Randall]

I’m unaltered (ie., unvaxed) and still kickin. Can you tell me the absolute difference in risk of death from covid between you and me? Assuming we are both under 50.

I’ve got ivermectin on hand in case I catch it. Zero risk of vaccine side effects. It’s a logical choice.

 

I don't have all day to unpack all the craziness in this post.

[max.bravo]

I don't have all day to unpack all the craziness in this post.

Which risk assessment methodology did you use to inform your choice? And if an institutional framework, how did you modify it to fit a personal health decision? And from where did you obtain data?

I used a modified version of the AHRA framework and the EPA framework for health risk assessment. It’s pretty simple- you plug in the inputs with your level of data certainty and it tells you what makes sense.

Go through the exercise pretending to be a public health official and you’ll see why they recommended vaccines to everyone.

Go through the exercise as an individual in good health (no comorbidities) under 50 and you’ll get a different result. 🤷🏾‍♂️

[Greg]

Delta variant cares a lot less about how young you are. Also, you're part of a society, it isn't just about you.

[Mike K.]

It also doesn’t seem to care if you have the vaccine.

[Victoria Watcher]

It also doesn’t seem to care if you have the vaccine.

I think it does in terms of serious cases. hospitalizations, ICU, and deaths. those are all lower for vaccinated people. even with the Delta variant.

[Greg]

It also doesn’t seem to care if you have the vaccine.

 

That's just not true. The info VW posted earlier showed locally about a 60x greater chance of ending up in the hospital if you are unvaccinated. 

[Rob Randall]

Which risk assessment methodology did you use to inform your choice? And if an institutional framework, how did you modify it to fit a personal health decision? And from where did you obtain data?

 

 

Yeah, still, if I get Delta I know my vaccines will almost guarantee a satisfactory outcome. I'm sure as hell not going to guessimate the dosage on some head lice pills that some crazy podcaster recommended. 

 

Pure insanity.

Edited by Rob Randall, 05 August 2021 - 09:47 AM.

[max.bravo]

Yeah, still, if I get Delta I know my vaccines will almost guarantee a satisfactory outcome. I'm sure as hell not going to guessimate the dosage on some head lice pills that some crazy podcaster recommended.

Pure insanity.

It’s horse dewormer, and it’s a paste tyvm 😁

[Victoria Watcher]

That's just not true. The info VW posted earlier showed locally about a 60x greater chance of ending up in the hospital if you are unvaccinated.

here:


A look at the vaccination status of people hospitalized with COVID-19 in BC proves this point. According to BC Ministry of Health statistics, between June 15 and July 15, 137 unvaccinated people landed in the hospital—just eight fully vaccinated individuals were hospitalized in that period.

https://www.capitald...th-wave-is-here

that does not seem to be 60x but it’s still significant.

Edited by Victoria Watcher, 05 August 2021 - 09:55 AM.

[Rob Randall]

It’s horse dewormer, and it’s a paste tyvm

 

I think you're pulling my pastern.

Edited by Rob Randall, 05 August 2021 - 09:53 AM.

[Greg]

here:


A look at the vaccination status of people hospitalized with COVID-19 in BC proves this point. According to BC Ministry of Health statistics, between June 15 and July 15, 137 unvaccinated people landed in the hospital—just eight fully vaccinated individuals were hospitalized in that period.

https://www.capitald...th-wave-is-here

that does not seem to be 60x but it’s still significant.

 

You have to factor in that far more people are vaccinated than unvaccinated. It might be more like 40x depending on how you calculate the percent vaccinated.