The doctor who was accused in 2020 of breaking New Brunswick's COVID-19 rules by failing to isolate, and of being the source of a deadly outbreak, is suing the province, the RCMP and Facebook's parent company.
Lawyers for Dr. Jean-Robert Ngola, 52, said Thursday they have filed their claim with the Court of Queen's Bench in Moncton — seven months after they announced their intention.
The document alleges, among other things, "institutional anti-Black systemic racism," abuse of power, negligence, defamation, malicious prosecution and a breach of the doctor's charter rights.
"This is a battle for rights, human dignity and against racism," Ngola told reporters in French during an online news conference from Louiseville, Que., where he now practises.
Joel Etienne, one of his lawyers, who is based in Toronto, said they expect the legal battle to be "needless and protracted."
https://www.cbc.ca/n...wsuit-1.6321845
The Vancouver Canucks COVID-19 outbreak continues, with star goalie Thatcher Demko and forward J.T. Miller testing positive for the virus via rapid tests on Thursday.
https://www.cbc.ca/s...covid-1.6321982
Researchers at UBC’s faculty of medicine have conducted the world’s first molecular-level structural analysis of the Omicron variant spike protein. The findings were published today in Science.
The analysis—done at near atomic resolution using cryo-electron microscopy—reveals how the heavily mutated Omicron variant attaches to and infects human cells.
“Understanding the molecular structure of the viral spike protein is important as it will allow us to develop more effective treatments against Omicron and related variants in the future,” said lead author Dr. Sriram Subramaniam (he/him), professor in UBC’s department of biochemistry and molecular biology. “By analyzing the mechanisms by which the virus infects human cells, we can develop better treatments that disrupt that process and neutralize the virus.”
https://www.eurekale...releases/940715
study of the day
AMES, Iowa – Iowa State University scientists may have uncovered an important clue that sheds light on why pigs don’t get sick when exposed to the coronavirus.
Studies since the start of the pandemic have noted that pigs can be infected by the virus if exposed to high doses, but the infection is self-limited and pigs don’t show clinical signs of disease nor do they transmit the virus to other animals. So Rahul Nelli, a research assistant professor of veterinary diagnostic and production animal medicine, and Luis Gimenez-Lirola, an associate professor of veterinary diagnostic and production animal medicine, set out to find out why in a newly published study in the academic journal Cell Death Discovery. What they found could lead to new ways to treat humans who contract COVID-19, the disease that results from infection by the virus SARS-CoV-2, said Nelli and Gimenez-Lirola.
Nelli and Gimenez-Lirola have studied how coronaviruses affect pigs for years. They’ve developed models that allow them to study in detail how viruses infect pigs and pig cells and how the cells respond to fight the infection. For the latest experiments, they introduced the virus to cultured porcine and human respiratory epithelial cells, which line most of the respiratory tract. They found the pig cells underwent apoptosis, or controlled cell death, in response to infection at a higher rate than human epithelial cells.
“When we looked under the microscope there was an interesting phenomenon going on inside the cells,” Nelli said. “The nuclei of the infected pig cells were starting to shred into fragments but not uninfected pig cells.”
That shredding of the nucleus is a telltale sign of apoptosis, which may be a key in helping pigs avoid symptoms after exposure to SARS-CoV-2. Triggering apoptosis early in the infection essentially causes minimal tissue damage and confines viral replication, thus limiting severe illness. Human cells can undergo apoptosis in response to coronavirus infection as well, but the study found human cells do so much less frequently than porcine cells. Pig cells are roughly 100 times more likely to undergo apoptosis than human cells, according to the study.
https://www.news.ias.../20/covidinpigs
https://www.scienced...20120125443.htm
COVID-19 Vaccines Do Not Cause Infertility
A new study has found that COVID-19 vaccination does not impair fertility—but males who become infected by the coronavirus may experience short-term reduced fertility.
https://www.bu.edu/s...se-infertility/
https://www.scienced...20120135142.htm
New Haven, Conn. — Millions of people around the world have received two shots of Sinovac, a Chinese-manufactured inactive vaccine that is used in 48 countries to help reduce transmission rates of COVID-19.
However, those vaccinations alone are of no help against the widely circulating Omicron variant, show a new study by researchers at Yale and the Dominican Republic. The results are published in the journal Nature Medicine.
An analysis of blood serum from 101 individuals from the Dominican Republic showed that Omicron infection produced no neutralizing antibodies among those who received the standard two-shot regimen of the Sinovac vaccine. Antibody levels against Omicron rose among those who had also received a booster shot of the mRNA vaccine made by Pfizer-BioNTech.
But when researchers compared these samples with blood serum samples stored at Yale, they found that even those who had received two Sinovac shots and a booster had antibody levels that were only about the same as those who’d received two shots of the mRNA vaccines but no booster shot. In other studies, the two-shot mRNA regimen without a booster has been shown to offer only limited protection against Omicron.
https://www.eurekale...releases/940813
Adele postpones Las Vegas concert series after half her crew gets COVID-19
British singer was set to begin a 3-month residency
https://www.cbc.ca/n...vegas-1.6322492
The FBI sought National Institutes of Health grant documents covering bat coronavirus research in Wuhan in spring 2020, according to emails obtained by The Intercept. The emails, released through ongoing litigation between The Intercept and the NIH, detail internal NIH conversations involving the New York-based nonprofit EcoHealth Alliance, which collaborated with the Wuhan Institute of Virology on research. The emails also contain previously unreported requests the agency made of EcoHealth Alliance as a condition for restoring a grant funding its research. While unable to provide some of the information requested by the agency, Peter Daszak, EcoHealth’s besieged president, fought fiercely to save the grant.
The new information gives an unprecedented window into the high-profile tussle between EcoHealth Alliance and the NIH, and underscores the agency’s tenuous grasp of the biosafety protocols in place in its research projects, even with a project that has since come under scrutiny for a possible link to the Covid-19 pandemic.
“There doesn’t seem to be transparent and accessible record-keeping of incident reporting,” said Filippa Lentzos, co-director of the Centre for Science and Security Studies at King’s College London, after viewing some of the emails. “That is very worrying and underscores the need for an overhaul of biosafety oversight in the United States.”
https://theintercept...-ecohealth-fbi/
Federal and state investigations into a large national chain of COVID-19 testing sites have turned up tests that were never labeled with patients' names, tests piled into trash bags stored for long periods at room temperature, tests that were never processed, and test results that were clearly fake.
Behind the testing sites are two Illinois-based companies: Center for COVID Control (CCC) and Doctors Clinical Laboratory, Inc., which is said to carry out COVID PCR testing for CCC. The two companies share the same address, though CCC is owned by Chicago-area couple Akbar Syed and Aleya Siyaj, while the clinical company is owned by Mohammed Shujauddin.
Together, the companies claim to provide rapid and PCR testing for COVID-19, with fast turnaround times and no appointments necessary. So far, they have collected more than 400,000 samples from over 300 locations across the US. And they have billed the federal government over $113 million for running many of those tests.
The companies are currently under investigation by the federal Centers for Medicare and Medicaid Services (CMS), as well as multiple states. On Wednesday, Minnesota Attorney General Keith Ellison filed a lawsuit alleging numerous counts of deceptive or fraudulent practices by the pair.
“When Minnesotans and people from around the country tested with these companies to keep themselves and their families safe, they trusted they would get correct results on time," Attorney General Ellison said in a statement. "I’m holding these companies accountable that sent back false or inaccurate results, when they sent them back at all, for deceiving Minnesotans and undermining the public’s trust in testing."
Alleged deceit
According to Ellison's lawsuit, Minnesota investigators found evidence of egregious fraud and documented numerous cases in which the consumers seeking COVID-19 tests were deceived. In Minnesota, CCC opened eight pop-up testing sites that claimed to provide rapid test results in 15 minutes, with an emailed confirmation of results within three hours and results of PCR tests within 24 to 48 hours.
CCC often missed those windows completely, and many consumers referenced in the lawsuit have yet to receive any results weeks to months after their tests. Former CCC employees told Minnesota investigators that many of those tests were simply never processed. The employees noted that test samples were piled up in garbage bags around CCC's office, without any organization or cold storage to keep the samples from degrading. According to federal inspections reported by NBC News, CCC employees didn't even label some samples with patients' names. Inspection documents from federal investigators noted that "51 out of 51 patient specimen tubes contained in the box [they examined] were blank.”
https://arstechnica....lled-feds-113m/
Four inmates at an Arkansas jail have filed a lawsuit against the facility and its doctor after they said they were unknowingly prescribed ivermectin to treat Covid-19 as a form of “medical experimentation” despite US health officials warning that the anti-parasitic drug should not be used for that purpose.
The Arkansas chapter of the American Civil Liberties Union filed the lawsuit on behalf of the men last week against Washington county jail, the Washington county sheriff, Tim Helder, and jail physician Dr Robert Karas. Last August, Helder revealed that the drug had been prescribed to patients with Covid-19.
“The lawsuit charges the defendants for administering ivermectin to incarcerated individuals without prior informed consent as to the nature, contents, or potential side effects of the drug,” the ACLU said in a statement last week.
Gary Sullivan, legal director of the ACLU of Arkansas, condemned Helder’s actions, saying: “No one – including incarcerated individuals – should be deceived and subject to medical experimentation. Sheriff Helder has a responsibility to provide food, shelter, and safe, appropriate care to incarcerated individuals.”
“Plaintiffs ingested incredibly high doses of a drug that credible medical professionals, the FDA, and the Centers for Disease Control and Prevention (CDC), all agree is not an effective treatment against Covid-19, and that if given in large doses is dangerous for humans,” the lawsuit said.
https://www.theguard...ovid-ivermectin